Nov 26, 2019 | Cancer Center News
Paul Hergenrother Paul Hergenrother, professor of chemistry and leader of the CCIL Program 2 (Cancer Discovery Platforms Bridging the Engineering-Biology Continuum), is one of eight Illinois faculty members elected as a 2019 Fellow of the American Association for the...
Nov 20, 2019 | Cancer Center News
The team includes, from left, graduate student Emily Geddes, pathobiology professor Gee Lau, chemistry professor Paul Hergenrother, postdoctoral researcher Hyang Yeon Lee, and postdoctoral researcher Erica Parker. Paul Hergenrother, professor of chemistry,...
Nov 2, 2019 | Cancer Center News, Student Spotlight
Sisi He, PhD Candidate, Molecular and Integrative Physiology TiMe 2016 CohortC*STAR 2017 Cohort What first led to your interest in cancer research? I studied Chemistry and Biochemistry at UW-Madison for my Bachelor’s degree. Afterward, I came here to pursue doctoral...
Nov 1, 2019 | Cancer Center News
CCIL Director Rohit Bhargava, Professor of Engineering, and member Jonathan Sweedler, the James R. Eiszner Family Endowed Chair in Chemistry and Director of the School of Chemical Sciences, made Analytical Scientist’s Power List Top 100. These individuals are...
Aug 1, 2019 | Cancer Center News, Student Spotlight
Hailey Knox, ChemistryTissue Microenvironment (TiMe) Program What is your research focus? I explore photoacoustic imaging, a technique where light is delivered into tissues, and certain compounds absorb it. When they release it as heat, we can detect that energy...
Jul 2, 2018 | Cancer Center News
DNA nanostructure flips lipids from one side of a lipid bilayer to the other more than 1,000 times as fast as natural enzymes called scramblases, researchers report (Nat. Commun. 2018, DOI: 10.1038/s41467-018-04821-5). Asymmetry in the lipid composition of the inner...
Jun 4, 2018 | Cancer Center News
Focal adhesions are large specialised proteins that are located in the area where a cell membrane meets the extracellular matrix (ECM), a collection of molecules surrounding the cells that provide support and regulate micromechanical signals to the cells. Examining...
Apr 9, 2018 | Cancer Center News
Image of Emerging Pathway of Doxorubin Cardiotoxicity. ABSTRACTDoxorubicin (DOX) is among the oldest and most-used chemotherapeutics. However, its use is limited by a cumulative dose that leads to cardiotoxicity. DOX is an anthracycline quinone that is known to...
Apr 3, 2018 | Cancer Center News
Image of William Arnold, a graduate student in biochemistry, and Aditi Das, an assistant professor of biochemistry and bioengineering graduate program. There are many anti-cancer therapeutics that are effective at killing cancer, but some can have serious side...
Mar 17, 2018 | Cancer Center News
This award is presented for outstanding, novel, and significant chemistry research, which has led to important contributions to the fields of basic cancer research, translational cancer research, cancer diagnosis, the prevention of cancer, or the treatment of patients...
Feb 27, 2018 | Cancer Center News
ABSTRACTThis study reports novel findings that link E-cadherin (also known as CDH1)-mediated force-transduction signaling to vinculin targeting to intercellular junctions via epidermal growth factor receptor (EGFR) and integrins. These results build on previous...
Nov 27, 2017 | Cancer Center News
Timothy Fan and Paul Hergenrother A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of patients with anaplastic astrocytoma, a rare malignant brain tumor, and glioblastoma multiforme, an aggressive late-stage cancer of the...
