The Cancer Center at Illinois’ (CCIL) Tumor Engineering and Phenotyping (TEP) Facility is the largest space dedicated to cancer research at Illinois The TEP is a campus shared resource supporting CCIL members and all other researchers at the university, as well as external users.


The TEP recently installed new equipment to further expand the TEP’s robust capacity to support a diverse array of experiments and analyses.

The TEP’s custom-made hypoxia chamber now houses the TEP’s Seahorse Analyzer. The hypoxia chamber enables realtime analysis of metabolic function, performed at a wide range of oxygen concentrations (including hypoxia) and allowing for analysis of in vitro cellular and organismal metabolic functions at relevant in vivo oxygen levels.

TEP Staff

Left to right: Huimin Zhang, Renee Walker, Hui Xu

The TEP’s new NanoGenerator™ Flex-M applies microfluidic approaches to synthesize nanoparticles (e.g., lipid nanoparticles or LNP) in a continuous mode. The system provides a wide throughput range from 1 to 12 mL, meeting a variety of applications from early screening to animal studies.

The TEP’s new PhenoCycler-Fusion System performs comprehensive spatial phenotyping across whole slides to detect protein and RNA in situ at single-cell resolution. The system is part of an integrated spatial biology workflow, including single-step tissue staining, image acquisition and on-board processing. It can analyze 100+ protein and RNA biomarkers for deep spatial phenotyping in 24 hours.


The TEP hired Renee Walker to support the TEP’s growing histology services. Renee comes to the TEP after two decades working as a histologist at Illinois’ College of Veterinary Medicine.

The TEP is a one-stop shop for biological and engineered materials analysis to accelerate cancer researchers’ discoveries.

Learn more at

Yun-Sheng Chen quote about the TEP