Research Program and Theme
- Program: Cancer Engineering and Biological Systems
- Theme: Mechanistic and Quantitative Biology
Research Focus
Supriya Prasanth’s laboratory is focused on understanding how replication initiation is coordinated with chromatin organization and cell cycle progression. Defects in accurate replication and faithful chromosome segregation cause genomic instability, a hallmark of all cancers. Using multi-disciplinary approaches, the Prasanth lab examines how replication initiation proteins, including the Origin Recognition Complex and ORC-associated (ORCA/LRWD1), regulate diverse cellular processes. and its involvement in cancer progression. Learn more about Supriya Prasanth’s lab.