Research Program and Theme
- Program: Cancer Engineering and Biological Systems
- Theme: Anticancer Chemistry
Research Focus
David Kranz’s lab been involved for many years in the discovery of immunotherapeutic approaches to cancer. The research program he leads is focused on the structure, function, and engineering of T cell receptors. The Kranz lab is interested in understanding the molecular basis of immune recognition by T cells, in tumor-targeting with T cells and T cell-directed vaccines, and in engineering protein- and cell-based therapeutics.