Bo Wang

Bo Wang

Associate Professor, Comparative Biosciences

Research

Bo Wang’s laboratory focuses on understanding the molecular mechanisms underlying lipid metabolism and how this contributes to human diseases such as cancer. His previous research has identified lysophosphatidylcholine acyltransferase 3 (Lpcat3) as a critical determinant of membrane phospholipid composition and biophysical properties. Lpcat3 catalyzes the incorporation of polyunsaturated fatty acids at the sn-2 site of lysophospholipids, giving rise to polyunsaturated phospholipids. The ability to manipulate membrane phospholipid composition in vivo by regulating Lpcat3 expression provides an unprecedented opportunity to study the consequences of changing the membrane composition in homeostasis and the pathogenesis of diseases in living animals.

Education

  • Ph.D., Ohio State University, 2012

Campus Affiliations