Research

2019 Seed Grant Program

The Cancer Center at Illinois Seed Grant Program is designed to foster additional collaborations that reach across the engineering and biology continuum and leverage research team results for submitting external multi-PI grants in the cancer area. The CCIL received 19 completed applications which were carefully reviewed and discussed by a panel of five reviewers, following a process similar to that used by NIH, and awards were given for both seed grants and planning grants. The Seed Grant Program will run annually and is designed to facilitate collaboration, build thematic research, and support data collection. Be on the lookout for the next request for proposals in Fall 2019.

Cancer Immunotherapies for Precision Medicine in the State of Obesity

Principal Investigator

  • Andrew Smith
    Associate Professor, Bioengineering
    217.300.5638
    smi@illinois.edu

Team

  • Erik R. Nelson
    Assistant Professor, Molecular and Integrative Physiology
    217.244.5477
    enels@illinois.edu
  • Wawrzyniec Dobrucki
    Assistant Professor, Bioengineering
    Head, Experimental Imaging Laboratory
    217.244.3938
    dobrucki@illinois.edu

 

Characterization of Oncogenic Noncoding RNAs in Breast Cancer Progression and Metastasis

Principal Investigator

Team

  • Auinash Kalsotra
    Assistant Professor, Biochemistry
    217.300.7654
    kalsotra@illinois.edu
  • Erik R. Nelson
    Assistant Professor, Molecular and Integrative Physiology
    217.244.5477
    enels@illinois.edu
  • Wawrzyniec Dobrucki
    Assistant Professor, Bioengineering
    Head, Experimental Imaging Laboratory
    217.244.3938
    dobrucki@illinois.edu

 

Deep Mutational Scanning of Receptor Tyrosine Kinases Involved in Cancer Using Transfer Learning Approaches

Principal Investigator

  • Diwakar Shukla
    Assistant Professor, Chemical and Biomolecular Engineering
    217.300.0021
    diwakar@illinois.edu

Team

  • Erik Procko
    Assistant Professor, Biochemistry
    Professor of Biophysics and Quantitative Biology
    217.300.1454
    procko@illinois.edu

 

Next Generation Cancer Imaging Using Super-Resolution Ultrasound Microscopy Combined with Photoacoustic Tomography

Principal Investigator

  • Pengfei Song
    Assistant Professor, Electrical and Computer Engineering
    217.300.9763
    songp@illinois.edu

Team

  • Yi Lu
    Professor, Chemistry
    217.333.2619
    yi-lu@illinois.edu
  • Liang Gao
    Assistant Professor, Electrical and Computer Engineering
    217.300.9930
    gaol@illinois.edu
  • Timothy Fan
    Professor, Veterinary Clinical Medicine
    217.333.5375
    t-fan@illinois.edu
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Planning grants are awards for $25,000 which are used to bring together faculty from multiple disciplines to develop collaborative ideas, workshops and/or programs or collect preliminary data over the course of one year.

A 3D In vitro Biomimetic Tumor Microenvironment Integrated with a Micro Sensor Platform

Principal Investigator

  • M. Taher A. Saif
    Professor, Mechanical Science and Engineering
    217.333.8552
    saif@illinois.edu

Team

  • Kimberly Selting
    Associate Professor, Veterinary Medicine
    217.333.5300
    seltingk@illinois.edu
  • Mohammed El-Kebir
    Assistant Professor, Computer Science
    217.333.0135
    melkebir@illinois.edu

 

Diet-Modified Efficacy of RAGE-Targeted Prostate Cancer Treatments

Principal Investigator

  • Wawrzyniec Dobrucki
    Assistant Professor, Bioengineering
    Head, Experimental Imaging Laboratory
    217.244.3938
    dobrucki@illinois.edu

Team

  • Erik R. Nelson
    Assistant Professor, Molecular and Integrative Physiology
    217.244.5477
    enels@illinois.edu
  • John W. Erdman
    Professor Emeritus, Food Science and Human Nutrition
    217.333.2527
    jwerdman@illinois.edu

 

Elucidating Mechanisms by which Environmental Toxicants Induce Liver Cancer

Principal Investigator

  • Auinash Kalsotra
    Assistant Professor, Biochemistry
    217.300.7654
    kalsotra@illinois.edu

Team

  • Joseph Irudayaraj
    Professor, Bioengineering
    217.300.0525
    jirudaya@illinois.edu
  • Jodi Flaws
    Professor, Comparative Biosciences
    217.333.7933
    jflaws@illinois.edu

 

Elucidating Premetastatic Niche-Induced Therapy Resistance Mechanisms in ER(+) Metastatic Breast Cancers

Principal Investigator

  • Zeynep Madak-Erdogan
    Assistant Professor, Food Science and Human Nutrition
    217.300.9063
    zmadake2@illinois.edu

Team

  • Roy Dar
    Assistant Professor, Bioengineering
    217.265.0708
    roydar@illinois.edu
  • Erik R. Nelson
    Assistant Professor, Molecular and Integrative Physiology
    217.244.5477
    enels@illinois.edu

 

Eradication of H. pylori with pH-sensitive Antimicrobial Polypeptides to Reduce Gastric Cancer

Principal Investigator

  • Jianjun Cheng
    Professor, Bioengineering
    217.244.3924
    jianjunc@illinois.edu

Team

  • Lin-Feng Chen
    Professor, Biochemistry
    217.333.7764
    lfchen@life.illinois.edu

 

Integrated Computational and CRISPR-Cas9 Imaging Platforms for Studying Noncoding Pathogenic Germline Variants and Somatic Mutations in Breast Cancer

Principal Investigator

Team

 

Listening Online and Listening Face-to-Face: Innovative Mixed-Method Approaches for Studying Cancer Communication in the New Media Environment

Principal Investigator

  • Kevin Chang
    Professor, Computer Science
    217.244.2919
    kcchang@illinois.edu

Team

 

Predicting Response to Cancer Immunotherapy Using a Subclone-Integrated Machine Learning Model of Neoantigen Processing, Presentation, and Recognition

Principal Investigator

  • Jian Peng
    Assistant Professor, Computer Science
    jianpeng@illinois.edu

Team

  • Mohammed El-Kebir
    Assistant Professor, Computer Science
    217.333.0135
    melkebir@illinois.edu
  • Hong Jin
    Assistant Professor, Biochemistry
    217.244.9493
    hjin@illinois.edu
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