Research Program and Theme
Cancer Engineering and Biological Systems | Mechanistic and Quantitative Biology
Research Focus
Prasanth Kannanganattu’s laboratory has significantly contributed to understanding lncRNA’s role in gene expression. His lab explores the molecular mechanism by which the oncogenic lncRNA, MALAT1, controls alternative splicing (AS) of pre-mRNA and utilizes hypoxia response in breast cancer cells as an experimental model system. The current application builds logically on his prior work, describing the role of lncRNAs in gene regulation and their involvement in cancer. His lab was the first to demonstrate the participation of MALAT1 in AS (alternative splicing) of pre-mRNAs.
Education
- Ph.D., Banaras Hindu University
Campus Affiliations
- Professor, Cell and Developmental Biology