Research Program and Theme
- Program: Cancer Technology and Data Science
- Theme: Molecular Measurement
Research Focus
Pablo Perez-Pinera has a broad background and extensive experience in genome engineering, gene editing, and regulation of gene expression with artificial transcription factors. Perez-Pinera’s work has been critical for understanding the activation of native gene expression using TALEs or CRISPR artificial transcription factors, and his lab has developed gene-editing tools to correct Duchenne muscular dystrophy and to generate tools targeting the ROSA26 locus for mouse transgenesis. The Perez-Pinera laboratory is actively developing next-generation genome engineering platforms to advance towards cures for genetic diseases, including using these techniques to create model cell lines to understand cancer progression and to develop therapies for glioblastoma. Learn more about Pablo Perez-Pinera’s lab.
Other Campus Affiliations
- Associate Professor, Biomedical and Translational Sciences
- Affiliate, Molecular and Integrative Physiology
- Associate Professor, Carl R. Woese Institute for Genomic Biology