Research Program and Theme
- Program: Cancer Engineering and Biological Systems
- Theme: Mechanistic and Quantitative Biology
Research Focus
Nicholas Wu’s lab mainly focuses on the biophysical characterization of antibody-antigen interaction. Through high-throughput screening and biophysical characterization of antibody variants, his lab’s research provides insights into the mechanisms of antibody binding to an antigen of interest and facilitates antibody engineering. While his previous antibody work has mostly been related to viruses, Wu’s current research interest has recently expanded to antibody-based therapeutics in cancer. Specifically, his lab is interested in discovering and optimizing antibodies that can potently inhibit tumor growth in vivo.
Learn more about Nicholas Wu’s lab.
Other Campus Affiliations
- Associate Professor, Biomedical and Translational Sciences
- Affiliate, Carl R. Woese Institute for Genomic Biology