Research Program and Theme
Cancer Engineering and Biological Systems | Anticancer Chemistry
Research Focus
Michael Spinella’s laboratory is focused on the molecular genetics of cancer, especially in the areas of mechanisms of tumorigenesis, cancer therapy, and drug resistance. One research focus is on uncovering mechanisms that account for the curability of metastatic testicular germ cell tumors in order to inform novel therapeutic strategies for advanced somatic solid tumors including glioblastoma and breast cancer. Other interests include the concept of differentiation therapy and the identification of mechanistic links between stem cell pluripotency, cancer, and response to chemotherapy. Spinella has a strong background in anticancer target identification and in molecular mechanisms of carcinogenesis, cancer therapeutics and chemoresistance.
Education
- Ph.D., Biochemistry, Albany Medical College
Campus Affiliations
- Professor, Comparative Biosciences
- Professor, Biomedical and Translational Sciences