Research
Lin-Feng Chen researches infections that cause gastric cancer and other types of cancers. His research has uncovered Helicobacter pylori, a common stomach infection, causes gastritis, peptic ulceration, and is the strongest risk factor for the development of gastric cancer. The Chen lab also studies the regulation and function of Bromodomain-containing protein 4 (Brd4) in cancer and immunity. It is a regulator of NF-κB-mediated inflammatory response and cancer development. Chen’s research has demonstrated that small molecules inhibiting Brd4 have strong anti-tumor and anti-inflammatory activities. His research will help develop new therapeutic cancer and inflammatory disease treatments.
Education
- Ph.D., Kyoto University, 1999
Campus Affiliations
- Professor, Biochemistry
- Professor, Carl R. Woese Institute for Genomic Biology