Research Program and Theme
- Program: Cancer Engineering and Biological Systems
- Theme: Anticancer Chemistry
Research Focus
Lin-Feng Chen studies infections that cause gastric cancer and other cancers. His research has uncovered that Helicobacter pylori, a common stomach infection, causes gastritis, peptic ulceration, and is the strongest risk factor for the development of gastric cancer. The Chen lab also studies the regulation and function of Bromodomain-containing protein 4 (Brd4) in cancer and immunity. It is a regulator of NF-κB-mediated inflammatory response and cancer development. Chen’s research has demonstrated that small-molecule inhibitors of Brd4 have strong anti-tumor and anti-inflammatory activities. His research will help develop new therapeutic approaches for cancer and inflammatory diseases. Learn more about Lin-Feng Chen’s lab.
Other Campus Affiliations
- Professor, Carl R. Woese Institute for Genomic Biology