Breakthrough Interdisciplinary Research. Life-Changing Impact.

A Complex Problem

Fighting cancer goes beyond a single field, perspective, or approach. The Cancer Center at Illinois combines expertise from multiple disciplines, fostering the creativity that leads to innovation in treatments, diagnostic tools, and prevention strategies. Below is a snapshot of the CCIL’s interdisciplinary research strategy.

Researcher using liquid nitrogen

Measuring Success

The CCIL monitors the effectiveness of efforts through member participationevents, case studies, progress in facilities and new equipment, development of clinical collaborations, and
translation to industry. The following metrics are crucial to evaluating our collaborative efforts.

26

New nembers since 2022

69%

Interdisciplinary publications from 2019-24

49%

Collaborative, peer-reviewed, multi-PI grants in 2024

>$100M

Awarded in new multi-PI centers since 2022

Collaboration Mechanisms

The CCIL places an emphasis on interdisciplinary research teams through the following mechanisms.

Organizing regular working group, research program, and organizational level meetings

Funding collaborative pilot projects and providing staff support to help progress

Facilitating collaborations in education and mentoring

Investing in facilities and SRs to address resource gaps

Developing clinical partnerships

Strategically recruiting, developing and supporting members across disciplines

Robust Membership

125

Faculty Researchers

6

Colleges/Schools

21

Department/Fields

Find Illinois scientists who are transforming cancer research.

Postdoctoral researcher Indrajit Srivastava, left, and electrical and computer engineering professor Viktor Gruev led a team of researchers developing new cancer imaging agents that can light up two cancer biomarkers when lit by one fluorescent wavelength.

Interdisciplinary Seed Grant in Action: CCIL Seed Grant Leads to NIH Grant Support

Project: Characterizing Oncogenic Noncoding RNAs in Breast Cancer Progression and Metastasis

Providing insight into long non-coding RNAs, which are often present in cancer cells, and heavily affect breast cancer progression, metastasis, and patient survival rates.

$250K

Initial Seed Grant

$1.25M

Resulting NIH Support

Kannanganattu V. Prasanth, professor of chemistry, with undergraduate research assistant David Song (standing) and post-doc Vidisha Pripathi. (pictured on computer screen are mammalian cell nuclei housing nuclear speckles.

Research Team

Kannanganattu Prasanth

Kannanganattu Prasanth

Professor, Cell & Developmental Biology

Auinash Kalsotra

Auinash Kalsotra

Professor, Biochemistry

Erik Nelson

Erik Nelson

Associate Professor, Molecular & Integrative Physiology

Wawrzyniec Dobrucki

Wawrzyniec Dobrucki

Associate Professor, Bioengineering

“The support from the CCIL seed grant and cross-campus collaborations helped answer key questions, created a much stronger proposal, and was instrumental in obtaining the R01,” Kannanganattu said. “The CCIL is a great platform to meet and discuss science, bringing people together with different areas of expertise.” — Kannanganattu Prasanth

Translating Interdisciplinary Research to the Clinic

The CCIL and the OSF HealthCare Cancer Institute are joining forces on the Breakthrough Engineering and Advanced Treatment of (BEAT) Cancer Research Initiative, a unique opportunity for interdisciplinary research teams to drive innovative cancer treatment and care solutions.

Exterior of the OSF HealthCare Cancer Center

Interdisciplinary Education

The CCIL’s undergraduate Cancer Scholar Program’s encourages interdisciplinary engagement with members and other students. Courses in the program are team-taught and require students undertaking research with a primary or collaborative member outside their home department.

An Educational Journey: Joy Chen

Joy Chen

Introduction to cancer research via researcHStart, an interdisciplinary program for high school students

5
Joy Chen

Undergraduate research via the Cancer Scholars Program and Mayo Clinic fellowship

5
Joy Chen

Now: Ph.D. candidate studying breast cancer at the University of California, Berkeley

“It’s rare to have a program for high schoolers with little experience and train them through an introduction to research.” — Joy Chen