Paul J.A. Kenis

Professor, Chemical and Biomolecular Engineering

Dr. Kenis received his BS in Chemistry from the Radboud University, Nijmegen, The Netherlands, in 1993 and his PhD in Chemical Engineering from the University of Twente, The Netherlands, in 1997. Then, he was a postdoctoral researcher at Harvard University with George Whitesides till 2000. Currently, he is a professor in and the Head of the Department of Chemical & Biomolecular Engineering at the University of Illinois, Urbana-Champaign. He is also the theme leader for Regenerative Biology and Tissue Engineering at Institute of Genomic Biology.

The Kenis research group explores the use of microfluidics to address interdisciplinary problems, including biomedical and fundamental biology applications. One of the major thrusts in the biomedical area is application of microreactors for synthesis of radiopharmaceuticals. These drugs are routinely used in diagnosis and treatment of many diseases, including cancer. The microreactor technology enables rapid, efficient, automated, reliable, robust, and safe way to synthesize radiolabelled biomolecules, thus potentially impacting the field of cancer diagnosis and treatment. Along with radiopharmaceutical synthesis, the Kenis research group is developing microfluidic technologies for other biomedical applications, such as screening of antibiotics and solid form screening of pharmaceuticals. The Kenis research group is also involved in application of microfluidics for basic biology studies, including crystallization of membrane proteins and inter-cellular signaling. For example, in collaboration with Gaskins and coworkers, intracellular redox-sensitive biosensors were developed, for example to study cancerous cells which are known to have a disrupted redox regulation.

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