Ann M. Nardulli

Photograph
Biography

Dr. Nardulli is a Professor in the Department of Molecular and Integrative Physiology at the University of Illinois at Urbana-Champaign. She completed her PhD in the Department of Physiology and Biophysics and performed postdoctoral work in the Department of Biochemistry at the University of Illinois at Urbana-Champaign. Dr. Nardulli’s research group uses molecular, cellular, and biochemical approaches to examine the expression of endogenous, estrogen-responsive genes in human breast cancer cells. Recently, her group assessed the expression of oxidative stress and DNA repair proteins in normal human mammary tissue, benign hyperplasia, ductal carcinoma in situ, and invasive breast cancer in order to identify proteins that may play a role in tumorigenesis and/or tumor progression.

Dr. Nardulli has had a long-term interest in breast cancer that has spanned her scientific career. She has served on review panels and received funding from the National Institutes of Health and the Department of Defense to study the regulation of gene expression in breast cancer cells, carried out numerous studies using human breast cancer cell lines to identify proteins that influence estrogen responsiveness, and assessed the expression of specific proteins in human mammary tissue and biopsies. Her current goal is to use a proteomic approach to identify therapeutic targets for treatment of triple negative breast cancer.

Keywords

Estrogen, estrogen receptor, breast cancer, oxidative stress response proteins, DNA repair proteins

More Information

Visit http://mcb.illinois.edu/faculty/profile/nardulli to learn more about Dr. Nardulli, including publication information.

*University of Illinois Cancer Center Member